Demi Moore, who is nominated for Best Actress at the 2025 Oscars, and Margaret Qualley, who plays a younger version of Moore's character in Coralie Fargeat's horror film 'The Substance,' each put their bodies on the line for the demanding shoot.

Demi Moore thought her four-decade Hollywood career might be over a few years ago. The actress, 62, battled negative thoughts about herself after a producer dismissed her as a "popcorn actress."

The Substance took theaters by storm, but the body horror film starring Demi Moore is not for the weak. Some viewers might prefer to watch it at home so they can take a breath and a walk around the block after witnessing French filmmaker Coralie Fargeat’s confrontational and explicit imagery.