Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone ...

Using an experimental technique new to the dengue field, researchers showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue type-3 to ...

Scientists have deciphered how the insulin molecule exploits a protective hinge to engage its primary binding site within the insulin receptor. "We discovered an essential mechanism for how insulin ...