Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage ...

The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians—controlling what enters, cleaning up waste, and ...

Peptide conjugation techniques are advancing CNS delivery of oligonucleotides, addressing blood-brain barrier challenges and improving therapeutic outcomes.

Healthy brain function relies on a steady supply of blood. Disruptions in blood flow are linked to major neurological conditions like stroke, Alzheimer's disease (AD), and traumatic brain injuries.

New noninvasive tools reveal that subtle shifts in brain blood flow and oxygen use may mirror key markers of Alzheimer’s risk ...

The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural ...

A brain mechanism may explain why approximately 40% of people with hypertension continue to have high blood pressure despite taking medication. The discovery reveals potential targets for new ...

Scientists develop a blood test that detects Alzheimer’s by measuring protein structural changes rather than protein quantity.

Scientists reverse Alzheimer's memory loss in mice by using NAD+ to restore brain energy, defying decades of research.

A major obstacle is the blood-brain barrier, which Kunwar described as similar to “Saran Wrap” surrounding every blood vessel in the brain. This barrier evolved to protect the brain from foreign ...