If your morning cup uplifts you, a China study involving almost half a million participants is confirming that pick-me-up.

Major depressive disorder (MDD) is a psychiatric condition characterized by persistent feelings of sadness, a loss of ...

A new randomized clinical trial from investigators at Mass General Brigham's Neuroscience Institute and Department of ...

Researchers have found that even after recovery, individuals who previously experienced depression may retain a heightened sensitivity to negative cues and face challenges in regulating responses to ...

A proof-of-concept study suggests the 5-HT4 receptor agonist prucalopride, which is approved for chronic constipation, ...

For the first time, Americans with depression will soon be able to use a prescription brain-stimulation device at home. The approval comes from the U.S. Food and Drug Administration and marks a major ...

Rose covers disability and mental health, and she helps write STAT’s daily Morning Rounds newsletter. Confidential tips can be sent to Rose on Signal at rosebroderick.11. Depression has many faces.

Researchers say a single intravenous ketamine infusion can rapidly relieve severe depression and suicidal thoughts when ...

Deep brain stimulation can significantly reduce depressive symptoms in some individuals. Knowing what to expect before and after the procedure may help you determine if it’s right for you. Deep brain ...

PPD remains one of the most disabling complications of childbirth, which is typically characterized by sadness, restlessness, impaired concentration, and sleep disturbances. Although PPD is considered ...

Brain stimulation therapies use electrical currents to alter the brain’s activity. They can treat conditions such as major depression and substance misuse disorder. However, side effects such as ...

New research in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging shows that the brain of individuals who have recovered from depression retains a heightened sensitivity to negative cues, ...