Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

In the course of early embryonic development, pluripotent stem cells first give rise to three lineages or ‘germ layers’, which then generate all cell types, tissues and organs of the human body, e.g.

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of ...

Huntington’s disease (HD) was the first neurological disorder to be linked to a mutation in a single gene—a discovery made more than 25 years ago. However, neither the pathogenic mechanisms leading to ...

Fredrik Lanner is in the Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Gynecology and Reproduction, Karolinska University Hospital, Stockholm, and ...