Anne van Schoonhoven is in the Departments of Pulmonary Medicine and of Cell Biology, Erasmus University Medical Center, Rotterdam 3015 GD, the Netherlands. Ralph Stadhouders is in the Departments of ...

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...

Researchers have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that ...

Scientists are hopeful it will improve understanding of how genes work, what goes wrong in disease, and how to fix it.

Through powerful high-resolution microscopy and precise biochemical methods, researchers at the Sloan Kettering Institute have seen for the first time how proteins and DNA come together to commence ...

Beam Therapeutics focuses on base editing technology, which allows for precise changes at the DNA level and potentially reduces off-target effects. Base editing has the versatility to correct a wide ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

CRISPR-Cas9 has been editing the human genome for the past decade. Although the types of edits have varied, an unsolved challenge has been the integration of large pieces of DNA without ...

CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes; to watch CRISPR enzymes respond to different genes, Leipzig University researchers ...