Open Heart

Discharge NT-proBNP predicts 2-year outcomes after TAVR but not after SAVR in preserved ejection fraction: a propensity-matched cohort study

Background Discharge N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a recognised prognostic marker after ...

Cardurion Pharmaceuticals Presents Phase 2 Results for Tovinontrine (CRD-750), a PDE9 Inhibitor, as a Novel Treatment for Heart Failure

REF Phase 2 clinical trial, tovinontrine demonstrated substantial reduction in NT-proBNP, a biomarker for heart failure, in patients ...
Medscape

NT-proBNP Testing for HFpEF Needs a BMI Makeover

Diagnostic thresholds of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for heart failure with preserved ejection fraction (HFpEF) in ambulatory patients with chronic dyspnearequire ...
Healio

Data on PDE9 inhibition in HF mixed; more research planned

Tovinontrine increased plasma cyclic guanosine monophosphate levels in patients with HF with reduced or preserved ejection ...