Otsuka’s Voyxact was granted accelerated approval from the FDA in November 2025 based on nine-month data.

Endothelin biology remains an attractive therapeutic target in IgA nephropathy where intrarenal endothelin-1 expression is upregulated and implicated in nephron loss through vasoconstriction, ...

Finerenone reduced kidney function decline and cardiovascular-kidney events in non-diabetic CKD. Find out more from the ...

The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the ...

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood. The kidney achieves these important ...

However, its role extends far beyond waste disposal, contributing to hormone regulation, blood pressure control, electrolyte ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...