The Week 10 NFL schedule kicks with the Denver Broncos vs. the Las Vegas Raiders in an AFC West showdown on 'Thursday Night Football.' The games starts at 8:15 p.m. ET, and daily Fantasy football players will have to be creative when looking for production since this game only has an over/under of 42.

NFL Week 10 betting spreads, lines, point totals for every game on NFL Week 10 schedule, with odds for favorites and underdogs in each NFL matchup.

With the bye week set to be complete, we're predicting the final nine games of the season. At the midway point of the 2025 NFL season, the Eagles (6-2) are currently the 2nd seed and behind the Packers, with their Week 10 matchup looming, and first in the NFC East.

We're nearly halfway through the 2025 regular season and some teams have a lot of work to do to clinch a postseason place.

As we go through the season, we will be posting updates of the draft order so you can see where the Bucs are, as well as others in the NFC South. Like we did with Summer scouting, we want Bucs fans to be the most knowledgeable fans.

A look at who is predicted to lead the NFL in rushing attempts in Week 10, plus accompanying player prop betting odds.