Understanding the mechanisms through which multicellular organisms regulate cell, organ and body growth is of relevance to developmental biology and to research on growth-related diseases such as ...
Tuberous sclerosis complex (TSC) is an autosomally inherited disorder with benign tumor formation in the brain, kidney, heart, lung, skin and eye (Cheadle et al., 2000; Dabora et al., 2001). The most ...
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target. The first paper, from Dr. Pier Paolo Pandolfi (BIDMC ...
Two independent papers identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target. Two independent papers in the August 15th issue of Genes & Development identify the ...