Sirtuins are a family of NAD⁺-dependent deacetylases that sense cellular energy status and coordinate responses to metabolic stress, inflammation and ageing. In articular cartilage, members of this ...

Sirtuin genes and the proteins they encode were already linked to longevity in yeast. Now, a previously overlooked member of the family has excited researchers who study aging At last, a member of the ...

Animals on the early branches of the tree of life, such as jellyfish and sea sponges, defy the usual conventions of aging. Some show abilities to regenerate damaged or missing tissues, halt or reverse ...

A new study has identified a protein found in fat cells that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk for ...

Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease. The study ...

A breakthrough in treating an aggressive form of prostate cancer could boost survival rates, according to new research.

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the ...

Jellyfish, sea sponges, amoebas and other animals on the early branches of the tree of life defy conventional aging. A new study reveals diversity of proteins called sirtuins in these animals compared ...