Blocking a tumor antioxidant restored T cell activity and made some resistant cancers more responsive to immunotherapy in ...
ZHOU Xuyu from the Institute of Microbiology of the Chinese Academy of Sciences (CAS), in collaboration with researchers from Beijing Ditan Hospital and Capital Medical University, has identified ...
An international research team led by Dr. Lucia Torres Fernández from the working groups of Professor Dr. Julie George and ...
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
KAIST researchers report that active vitamin A metabolite ATRA reduces CD8 T cell exhaustion in brain tumors and enhances ...
A new Stem Cell Reports study describes a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs). The work, which was done by scientists at Boston University’s ...
Researchers found that ATRA reduced terminal exhaustion in CD8+ T cells and enhanced anti-PD-1 therapy, improving tumor control and survival in glioma models.