rmdopen.bmj2h
Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis
Objectives Interstitial lung disease associated with rheumatoid arthritis (RA-ILD) is linked to high mortality. Currently, effective screening tools are lacking. We assessed the role of symptoms and ...
rmdopen.bmj3d
Targeting the IL-17A pathway for therapy in early-stage tendinopathy
Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic burden with high unmet medical needs. Recent clinical evidence suggests ...
rmdopen.bmj3d
Patients with ankylosing spondylitis present a distinct CD8 T cell subset with osteogenic and cytotoxic potential
Correspondence to Dr Mariagrazia Uguccioni; mariagrazia.uguccioni{at}irb.usi.ch; Dr Valentina Cecchinato; valentina.cecchinato{at}irb.usi.ch Conclusions Our results shed light on a new molecular ...
rmdopen.bmj4d
SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren's syndrome
Objectives To evaluate the interferon (IFN) biomarkers sialic acid binding Ig like lectin 1 (SIGLEC1, CD169) and IFN-γ-inducible protein-10 (IP-10) in patients with primary Sjögren's syndrome (pSS).
rmdopen.bmj6d
From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?
It is believed that therapy for rheumatoid arthritis (RA) is the most effective and beneficial within a short time frame around RA diagnosis. This insight has caused a shift from research in patients ...
rmdopen.bmj7d
Serum inflammatory biomarkers fail to identify early axial spondyloarthritis: results from the SpondyloArthritis Caught Early (SPACE) cohort
Introduction Decreasing the diagnostic delay in axial spondyloarthritis (axSpA) remains a major challenge. Here, we assessed the value of serum inflammatory biomarkers to distinguish early axSpA from ...
rmdopen.bmj11mon
Triple positive profile in antiphospholipid syndrome: prognosis, relapse and management from a retrospective multicentre study
Objective Antiphospholipid syndrome (APS) is defined by the association of thromboembolic and/or obstetrical clinical manifestations and the presence of antiphospholipid antibodies. The objective of ...
rmdopen.bmj10mon
Obesity is a risk factor for poor response to treatment in early rheumatoid arthritis: a NORD-STAR study
Objective This report from the NORD-STAR (Nordic Rheumatic Diseases Strategy Trials and Registries) trial aimed to determine if obesity is associated with response to conventional and biological ...
rmdopen.bmj2mon
Lymphoma complicating rheumatoid arthritis: results from a French case–control study
Objectives To study the characteristics of B-cell non-Hodgkin’s lymphoma (NHL) or Hodgkin lymphoma complicating rheumatoid arthritis (RA) and to identify RA-related factors associated with their ...
rmdopen.bmj1y
Four trajectories of 24-hour urine protein levels in real-world lupus nephritis cohorts
Objectives A 24-hour urine protein (24hUP) is a key measurement in the management of lupus nephritis (LN); however, trajectories of 24hUP in LN is poorly defined. Methods Two LN cohorts that underwent ...
rmdopen.bmj10mon
Association between sinusitis and incident rheumatic diseases: a population-based study
Objectives To determine whether antecedent sinusitis is associated with incident rheumatic disease. Methods This population-based case–control study included all individuals meeting classification ...