Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

Sudden leg weakness can occur with an injury or due to a serious underlying medical condition, such as multiple sclerosis, a stroke, or other health conditions. You may experience additional symptoms.