Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

Swelling in any part of the body, especially in the legs, can be an alarming sign. Swelling in the legs, also known as edema, occurs when excess fluid accumulates in the tissues of the lower ...

Leg shaking can be caused by anxiety, which makes your body feel like it's in danger and causes adrenaline to affect your muscles. Many medicines, like those for depression and allergies, can cause ...

Stretch your calf and thigh muscles before bed to help prevent leg cramps at night. Drinking at least six to eight glasses of water daily may help prevent leg cramps caused by dehydration. Pregnant ...

In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF researchers found NfL in the bloodstream of patients who would ...

Detection of certain auto-antibodies flagged patients with scleroderma (also known as systemic sclerosis) who were especially likely to develop pulmonary hypertension over long-term follow-up, a ...

Please provide your email address to receive an email when new articles are posted on . Data from two large U.S. cohorts showed more than 30% of patients with SSc demonstrated an initial symptom other ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

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Scleroderma is an autoimmune condition that primarily causes thickening of your skin. For some people, bladder or urinary problems may also develop. Some treatments for scleroderma may also cause ...

Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating ...

An investigational drug for multiple sclerosis from Io Therapeutics has restored leg mobility and myelin nerve coatings in mice, the biotech announced Dec. 23. The Texas-based company conducted the ...