Senator Lindsey Graham, the South Carolina Republican who relishes being in the middle of the action, is leapfrogging the House G.O.P., which is still tied in knots over a budget blueprint.

Now, pharmaceutical research that may take years and cost billions can be done more efficiently.

The Republican effort in Congress to pass President Donald Trump's energy, border and tax plans hit a new snag on Tuesday as House Speaker Mike Johnson (R-LA) effectively shut down efforts by Senate Republicans to go around him and revise the legislative approach.