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The 2016 WHO classification of tumors of the central nervous system has for the first time incorporated molecular features in the classification of diffuse gliomas. Astrocytomas are classified as isocitrate dehydrogenase (IDH) mutant or IDH wild type based on IDH genotype and they lack 1p19q codeletion. Approximately 70%–80% of WHO Grades II and III astrocytomas possess IDH mutations and the rest are IDH wild type. Diffuse astrocytomas with IDH mutations are regarded as the better prognostic gro
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