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Sleep is fundamental in regulating the hypothalamic-pituitary-adrenal axis, which is involved in growth hormone (GH) release. During deep (slow-wave) sleep, there is an increase in GH secretion. This peak of GH during sleep is essential for growth and muscle development, as well as tissue regeneration and repair. GH has a strong association with brain activity during deep sleep and plays a role in maintaining tissue homeostasis. Furthermore, GH has been identified as being one of the potential m
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